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KMID : 0361120100240030173
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Korean Journal of Transplantation
2010 Volume.24 No. 3 p.173 ~ p.181
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A Renal Transplantation and Hemodialysis Cost-Utility Analysis in Patients with End-Stage Renal Disease
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Kim Soon-Il
Kim Yu-Seun
Kim Myoung-Soo
Park Eun-Cheol
Jeon Kyung-Ok
Son Sun-Young
Hahm Myung-Il
Lee Hoo-Yeon
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Abstract
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Background: The purpose of this study was to examine the cost-effectiveness of renal transplantation and hemodialysis among end-stage renal disease patients.
Methods: Empirical data on treatment costs were collected from five hospitals in Korea. We used European Renal Association-European Dialysis and Transplant Association registry data for transition probability. Quality adjusted life year (QALY) values were derived from the literature. A Markov model was used for predicting the cost utility of transplantation and hemodialysis over a 10-year period.
Results: Renal transplantation was less costly and resulted in a better outcome than hemodialysis. The cost per QALY gained was 19,450 thousand won in transplantation patients, whereas it was 36,514 thousand won per QALY gained in hemodialysis patients.
Conclusions: Although the cost of the first year after transplantation was expensive, transplantation was more effective over 2 years and was less costly than hemodialysis. The results suggest that transplantation is more cost-effective than hemodialysis in Korea.
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KEYWORD
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Cost-effectiveness analysis, Cost-utility analysis, Renal transplantation, Hemodialysis, End-stage renal disease (ESRD)
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